Best Formula for Breastfed Babies (2025 Guide): Expert Tips & Top Picks – Willow Pump Skip to main content
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What is the Best Formula for Breastfed Babies?

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Updated November 2025

Choosing a formula for your precious breastfed baby can feel like navigating a maze with no map. The sheer number of options and the fear that your little one might reject them can leave you scratching your head. But fear not; we're here to help you unravel the mystery of selecting the best formula for your breastfed baby.

How to Choose the Best Formula for a Breastfed Baby

The formula market is flooded with options all claiming to be the "closest to breastmilk." So, where do you begin?

The best formula for breastfed babies depends on your baby’s digestion, preferences, and dietary needs. Top-rated options like Enfamil Enspire and Bobbie Organic offer complete nutrition and gentle blends designed to closely mimic breast milk. Start by consulting your pediatrician, who can provide tailored advice based on your baby's needs. If your child has allergies or specific dietary requirements, your pediatrician may recommend a special formula.

For a comprehensive guide on choosing the right formula, check out our blog.

Top Formulas That Are Closest to Breast Milk

Here's a list of some of the top brands known for their "closest to breastmilk" formulas:

  • Formula 1: Enfamil Enspire: Enfamil Enspire is formulated to provide complete nutrition and includes lactoferrin, which is also found in breast milk. It's designed to support brain development and has a gentle protein blend that's easy on little tummies.

  • Formula 2: Similac Pro-Advance: Similac Pro-Advance is known for its OptiGRO blend, which includes DHA, lutein, and vitamin E for brain and eye development. It's a popular choice for moms looking for a formula that's as close to breastmilk as possible.

  • Formula 3: Gerber Good Start Gentle: Gerber Good Start Gentle is designed for easy digestion with probiotics. It's a gentle formula that's free from genetically engineered ingredients and can be a great choice for babies with sensitive tummies.

  • Formula 4: Earth's Best Organic Infant Formula: For parents who prefer an organic option, Earth's Best Organic Infant Formula is a go-to choice. It's made with non-GMO ingredients and includes DHA and ARA for brain and eye development.

  • Formula 5: Holle Organic Infant Formula: Holle Organic Infant Formula is imported from Europe and is known for its high-quality, organic ingredients. It's a favorite among parents who prioritize organic and biodynamic farming practices.

  • Formula 6: Bobbie Organic Whole Milk Infant Formula: Bobbie's Organic Whole Milk Infant Formula is the first and only certified USDA organic whole milk infant formula in the US, with naturally-occurring MFGM from milk fat and a reduced volume of plant-based oils.

Formula Name

Key Benefits

Ideal For

Notable Ingredients

Enfamil Enspire

Closest to breast milk

Brain & immune support

DHA, lactoferrin

Similac Pro-Advance

Balanced nutrition

General use

DHA, lutein, vitamin E

Gerber Good Start Gentle

Easy digestion

Sensitive tummies

Probiotics

Earth’s Best Organic

Organic preference

Eco-conscious parents

Non-GMO, DHA

Bobbie Organic

Whole milk formula

U.S. organic certified

MFGM, milk fat

How to Know If You Picked the Wrong Formula

Picking the wrong formula can feel like a guessing game, but your baby will give you some telltale signs. Keep an eye out for signs of indigestion, such as excessive gas or fussiness during and after feeds.

If your baby starts refusing to eat or experiences abnormal fussiness, it might be time to reconsider the formula. Funky poops, like diarrhea or constipation, can also be indicators that the formula isn't agreeing with your baby's tummy.

Remember, it's all about finding the right fit for your little one's needs.

Willow Supports Every Feeding Journey

No matter which formula you choose for your breastfed baby, Willow is here to support you on your feeding journey. Our blog is a valuable resource for parents, no matter what path you decide to take. Whether it's breastfeeding, formula feeding, or a combination of both, we're here to provide information, guidance, and a supportive community to help you navigate parenthood with confidence. Explore the Willow blog today and discover a world of knowledge and connection.

In the end, remember that the best formula is the one that ensures your baby is healthy, happy, and thriving. Trust your instincts, consult your pediatrician, and cherish every moment of this incredible journey with your little one.

FAQs About Choosing Formula for Breastfed Babies

1. What type of formula is closest to breast milk?
Formulas like Enfamil Enspire and Similac Pro-Advance are designed to closely mimic breast milk, offering nutrients such as DHA, lutein, and lactoferrin that support brain and immune development.

2. Can I combine breastfeeding and formula feeding?
Yes. Many parents successfully supplement breast milk with formula, especially during transitions back to work or when milk supply fluctuates. Always introduce formula gradually to help your baby adjust.

3. How can I tell if a formula isn’t right for my baby?
Watch for signs like excessive gas, fussiness, constipation, diarrhea, or refusal to eat. If these persist, talk to your pediatrician about switching to a gentler or hypoallergenic formula.

4. Are organic baby formulas better for breastfed babies?
Not necessarily better, but organic formulas—like Earth’s Best or Bobbie Organic—can be a great choice for parents who prefer non-GMO, pesticide-free ingredients. What matters most is your baby’s comfort and tolerance.

5. How do I choose the best formula for my baby’s needs?
Start with your pediatrician’s recommendation, consider your baby’s digestive comfort, allergies, and feeding habits, and don’t be afraid to try a few options to find the best fit.